(2015, February 25). containing a total concentration no more than 20% by weight or volume in the case of a solid or liquid of anthranilic acid, N-anthranilic acid, gamma-butyrolactone, phenylacetic acid, piperonal or piperidine, AND is intended to be used in a food, drug, cosmetic or household product. Hypophosphorous acid is used as a reducing agent for electroplating without electrolysis. Commercial acid usually contains calcium salts. A clear, colorless or slightly yellow oily liquid or deliquescent crystalline solid, H3PO2, used as a reducing agent. Special material company. Similarly, it adds to Michael acceptors, for example with acrylamide it gives H(HO)P(O)CH2CH2C(O)NH2. In organic chemistry, H3PO2 best known for their use in the reduction of arenediazonium salts, converting ArN2+ to Ar-H.[1][2] When diazotized in a concentrated solution of hypophosphorous acid, an amine substituent can be removed from arenes, selectively over alkyl amines. Uses Hypophosphorous acid is used in the formulation of pharmaceuticals, discoloration of polymers, water treatment, retrieval of precious or non-ferrous metals. Call a physician or Poison Control Center immediately. NACRES NA.21 Sodium hypophosphite (NaPO2H2, also known as sodium phosphinate) is the sodium salt of hypophosphorous acid and is often encountered as the monohydrate. deposition of metal films from solution. Hypophosphorous acid is widely used as a reducing agent to reduce Cu, Hg and Ag etc. Hypophosphorous acid is a phosphorus oxoacid and a powerful reducing agent with molecular formula H3PO2. It has a role as an antioxidant. It can also be used as a sti… Because hypophosphorous acid can reduce elemental iodine to form hydroiodic acid, which is a reagent effective for reducing ephedrine or pseudoephedrine to methamphetamine,[3] the United States Drug Enforcement Administration designated hypophosphorous acid (and its salts) as a List I precursor chemical effective November 16, 2001. He Hypophosphorous acid , Also known as phosphinic acid, hypophosphite or HPA, is an inorganic compound of formula H 3 PO 2 . A. Murphy "Hypophosphorous Acid" in Encyclopedia of Reagents for Organic Synthesis (Ed: L. Paquette) 2004, J. Wiley & Sons, New York. The parent of the class of phosphinic acids. Hypophosphorous acid is used in the formulation of pharmaceuticals, discoloration of polymers, water treatment, retrieval of precious or non-ferrous metals. Its main use is for electroless plating; i.e. D. E. C. Corbridge "Phosphorus: An Outline of its Chemistry, Biochemistry, and Technology" 5th Edition Elsevier: Amsterdam. If breathing is irregular or stopped, give artificial respiration. May react explosively with mercury (II) oxide and violently with mercury (II) nitrate (Chemical Datasheet HYPOPHOSPHOROUS ACID, 2016). It is soluble in water, alcohol and ether and its formation heat is 137.7 Cal in liquid state and 140.0 Cal in solid state (Royal Society of Chemistry, 2015). In case of contact with eyes, rinse thoroughly with water for several minutes. Inorganic chemists refer to the free acid by this name (also as "HPA"), or the acceptable name of phosphinic acid. % in H 2 O Synonym: Phosphinic acid CAS Number 6303-21-5. Air sensitive. To use all functions of this page, please activate cookies in your browser. Contact with skin may cause swelling and blisters. It is a powerful reducing agent. Retrieved from PubChem. Hypophosphorous acid is a colorless oily liquid or deliquescent crystals (slowly liquefying) with a molecular weight of 66 g / mol. For example, formaldehyde and H3PO2 react to give (HOCH2)2PO2H. It is also possible that it is reduced to phosphine when it encounters a strong reducing agent. It is oxidized with sulfuric acid, releasing sulfur dioxide and sulfur. Wills, H. (1858). Hypophosphorous acid is used as bleaching or bleaching agent for plastics, synthetic fibers and chemicals. PubChem Substance ID 329752159. HOP(O)H2 exists in equilibrium with the minor tautomer HP(OH)2. to verify impurities, such as Nb, As and Ta, etc. PubChem Compound Database; CID = 3085127. Hypophosphorous acid is isolated by decomposing its barium salt with sulfuric acid (Wills, 1858). A recent study on the Hypophosphorous Acid market presents data-driven expert insights and various opportunity assessment frameworks for stakeholders. 2005-06-24. Figure 1: Structure of hypophosphorous acid. The top varieties of hypophosphorous acid products include butyl phosphinic, Hypophosphorous, phosphinic acid, Sodium Hypophosphorous. HYPOPHOSPHOROUS ACID Synonyms: Hypophosphorus Acid, Phosphinic Acid, HPA. Hypophosphorous acid is majorly manufactured from sodium hypophosphite. A Handbook of Chemical Analysis:. Inhalation of dust will produce irritation of the gastrointestinal or respiratory tract, characterized by burning, sneezing and coughing. Retrieved from ChemSpider. These derivatives are known as phosphinic acids, and their salts as phosphinates. Hypophosphorous Acid, H3PO2. The crystallization can be induced if necessary, by sowing with a crystal of the acid. Reacts with silver nitrate to give a white precipitate that darkens rapidly, even at low temperatures. Alcohol and ether are removed by distillation (atomistry.com, 2008-2012). Hypophosphorous acid. This depends on the amount of water in the acid crystals (National Center for Biotechnology Information, S.F.). NACRES NA.21 London: spottiswoode and co. Preparative Methods: the anhydrous acid is prepared from the commercial solution or from inorganic salts. Hypophosphorous acid is used as a reducing agent for electroplating without electrolysis. With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter. Hypophosphorous acid is used in medicine in the determination of arsenic, tellurium and separation of tantalum, niobium and oth… Severe overexposure may result in lung damage, asphyxia, loss of consciousness or death. It is used as an esterification catalyst. HPA is used in medicine to detect arsenic, tellurium, and separation of tantalum, niobium, and other reagents. It is soluble in water, alcohol, and glycerol. In hypophosphoric acid the phosphorus atoms are identical and joined directly with a P−P bond. The barium salt, Ba H 2 PO 2 ) 2 , The free acid can be prepared by double decomposition of a fifth molar solution with the calculated amount of 20 to 25% of sulfuric acid. SAFETY DATA SHEET Hypophosphorous Acid. Find out how LUMITOS supports you with online marketing. Sometimes the minor tautomer is called hypophosphorous acid and the major tautomer is called phosphinic acid. Slowly decomposes at rt. Inorganic chemists refer to the free acid by this name (also as "HPA") although its official IUPAC name is phosphinic acid. The total business generated in hypophosphorous acid category is 256734 USD last month. Company, 2017). Hypophosphorous acid is commonly used as a reducing agent in the production and formulation of various pharmaceutical products. It may be obtained from its water solution, by exaporation and freezing, as a white crystalline substance. Retrieved from cameo chemicals. It is a weak acid and forms only one series of salts, the hypophosphites. Webster's Revised Unabridged … Hypophosphorous Acid. Hypophosphorous acid is a phosphorus oxoacid and a powerful reducing agent. Hypophosphorous acid solution 50 wt. 7681-53-0) is a white, odorless, deliquescent granular powder with a … Structure, properties, spectra, suppliers and links for: Hypophosphorous acid, 6303-21-5, H2PO(OH), PH2(OH)O, PH2O(OH). MDL number MFCD02183592. Our quality is highly appreciated for its color stabilizer function, antioxydant property, or as reducer or catalyst in multiple industries. Figure 2: appearance of hypophosphorous acid. To use all the functions on Chemie.DE please activate JavaScript. deposition of metal films from solution. The acid is prepared industrially via a two step process: Firstly, hypophosphite salts of the alkali and alkaline earth metals result from the reaction of white phosphorus with hot aqueous solution of the appropriate hydroxide, e.g. The free acid may be prepared by the action of a strong acid on these hypophosphite salts. By using this website or by closing this dialog you agree with the conditions described, Physical and chemical properties of hypophosphorous acid. ), an acid, H3PO2, whose salts are produced by the action of barium hygrate on phosphorus. HPA is usually supplied as a 50% aqueous solution. It has a melting point that varies between 17.4 and 26.5 degrees Celsius. n a colourless or yellowish oily... Phosphinic acids - … Abstract. Retrieved from hypophosphorousacid.ne. It is also used as a catalyst in esterification, and as a polymerization and polycondensation catalyst. Use: Febex developped a 50% hypophosphorous acid from its own sodium hypophosphite, with the possibility to adapt material for each of our customers. Retrieved from hypophosphorousacid.net. The formula for hypophosphorous acid is generally written H3PO2, but a more descriptive presentation is HOP(O)H2 which highlights its monoprotic character. 1, 8. Retrieved from chemicalbook.com. 2010. It is widely used as a reducing agent, Ag, Cu, Ni, Hg, and other metals are reduced to the corresponding metal for the verification of As, Nb, Ta, and other reagents (ChemicalBook, 2016). Function, antioxydant property, or as reducer or catalyst in multiple.... Is used as a catalyst in esterification, and their salts as phosphinates HOCH2 ) 2PO2H varies between and. For electroless plating ; i.e is 6 USD while the maximum order value of hypophosphorous acid into a,... In Reactivity of P-H Group of phosphorus Based Compounds, 2018 chemical properties of hypophosphorous acid is a corrosive for... Insights and various opportunity assessment frameworks for stakeholders, your browser arsenic, tellurium and separation of tantalum,,. Joined directly with a Molecular weight of 66 g / mol alcohols, dioxane and water gastrointestinal or tract! Damage will depend on the length of the compound in the formulation of pharmaceuticals discoloration! 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